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Overview

Publications

  • Sangrador I, Molero X, Campbell F, Franch-Exposito S, Rovira-Rigau M, Samper E, Dominguez Fraile M, Fillat C, Castells A, Vaquero EC
    Zeb1 in stromal myofibroblasts promotes Kras-driven development of pancreatic cancer.
    Cancer Res. 2018 Feb 28. pii: 0008-5472.CAN-17-1882.
    DOI: 10.1158/0008-5472.CAN-17-1882.
    IF: 9,13
  • Keller J, Bassotti G, Clarke J, Dinning P, Fox M, Grover M, Hellstrom PM, Ke M, Layer P, Malagelada C, Parkman HP, Scott SM, Tack J, Simren M, Tornblom H, Camilleri M
    Expert consensus document: Advances in the diagnosis and classification of gastric and intestinal motility disorders.
    Nature Reviews Gastroenterology & Hepatology
    Nat Rev Gastroenterol Hepatol. 2018 May;15(5):291-308.
    DOI: 10.1038/nrgastro.2018.7. Epub 2018 Apr 6.
    IF: 16,99
  • Rodino-Janeiro BK, Martinez C, Fortea M, Lobo B, Pigrau M, Nieto A, Gonzalez-Castro AM, Salvo-Romero E, Guagnozzi D, Pardo-Camacho C, Iribarren C, Azpiroz F, Alonso-Cotoner C, Santos J, Vicario M
    Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction.
    Sci Rep. 2018 Feb 2;8(1):2255
    DOI: 10.1038/s41598-018-20540-9.
    IF: 4,12
  • Gomez-Hurtado I, Gimenez P, Garcia I, Zapater P, Frances R, Gonzalez-Navajas JM, Manichahn C, Ramos JM, Bellot P, Guarner F, Such J
    Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis.
    Liver Int. 2018 Feb;38(2):295-302.
    DOI: 10.1111/liv.13551. Epub 2017 Sep 13
    IF: 4,5
  • Huaman JW, Mego M, Manichanh C, Canellas N, Canueto D, Segurola H, Jansana M, Malagelada C, Accarino A, Vulevic J, Tzortzis G, Gibson G, Saperas E, Guarner F, Azpiroz F
    Effects of Prebiotics vs a Diet Low in Fodmaps in Patients with Functional Gut Disorder
    Gastroenterology. 2018 Oct;155(4):1004-1007.
    DOI: 10.1053/j.gastro.2018.06.045. Epub 2018 Jun 30.
    IF: 20,773
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Group Leader: Fernando Azpiroz Vidaur

In 2018 the group has continued the research program on digestive sensations in functional gut symptoms, by correlating physiological parameters with conscious sensations under different clinical and experimental conditions. Within this framework he role of microinflammation and gut microbiota has been addressed. Furthermore, the research program on the factors that determine the biological responses to food and diet has been expanded. A key aim of the program is the identification of innovative noninvasive biomarkers for the diagnosis, prevention and management functional gut disorders. To note, the group has maintained a high level of productivity (see publications), research funding (see research projects), networking (collaborative studies) and has attracted considerable mediatic interest in television, radio and press.

 

VHIR Annual Report 2018