Vascular Biology and Metabolism (VAM)

Overview

The Vascular Biology and Metabolism (VAM) area was created to enable a comprehensive, cooperative and multidisciplinary approach to research, development and transference of solutions for a group of diseases that are the leading cause of morbidity and mortality in the world: cardio- and neurovascular diseases, diabetes-metabolic syndrome and kidney failure.

This area also includes a group focused on Ophtalmology research and the Medical Molecular Imaging multidisciplinary group.

Publications

209

total

1181.950

impact factor

5.655

average impact factor

Group Leaders: David García-Dorado García
This Annual Report is in memory of our beloved group leader and former VHIR’s Director Dr. David García-Dorado García who passed away in August, 2019. Dr. Ignacio Ferreira recognizes his excellent career in this article

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During 2018, a large multidisciplinary cooperative project on the stratification of cardiovascular risk in diabetic patients (PRECISED) with 8 VHIR groups leaded by the Group on Cardiovascular Diseases has been finished, and ambitious independent multicenter clinical trials on aortic disease (BICATOR) and myocardial infarction (COMBAT-MI) leaded by our group have been almost completed. Important articles have been published on ischemic heart disease (relation to cardiac ageing, risk factors, management of acute events), Marfan syndrome, arrhythmias and congenital heart disease, as well as in transversal research lines, as cardiac imaging (4D-Flow in cardiac NMR studies) or clinical epidemiology (cost-effectiveness, risk stratification). Important advancements have been made in the transference of knowledge to the industry and the society, as the development of a new treatment against ischemia-reperfusion injury and adverse myocardial remodeling based on the inhibition of calpains.

91

total

593^.286

impact factor

6^.520

average impact factor

SELECTED ARTICLES

Davidson SM, Ferdinandy P, Andreadou I, Bøtker HE, Heusch G, Ibáñez B, Ovize M, Schulz R, Yellon DM, Hausenloy DJ, Garcia-Dorado D; CARDIOPROTECTION COST Action (CA16225).
Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week.
J Am Coll Cardiol. 2019 Jan 8;73(1):89-99.
doi: 10.1016/j.jacc.2018.09.086. Review. PubMed PMID: 30621955.
IF:16,834
Ruiz-Meana M, Minguet M, Bou-Teen D, Miro-Casas E, Castans C, Castellano J, Bonzon-Kulichenko E, Igual A, Rodriguez-Lecoq R, Vázquez J, Garcia-Dorado D.
Ryanodine Receptor Glycation Favors Mitochondrial Damage in the Senescent Heart.
Circulation. 2019 Feb 12;139(7):949-964.
doi: 10.1161/CIRCULATIONAHA.118.035869.
PubMed PMID: 30586718.
IF: 18,881
Teixido-Tura G, Forteza A, Rodríguez-Palomares J, González Mirelis J,Gutiérrez L, Sánchez V, Ibáñez B, García-Dorado D, Evangelista A. Losartan Versus.
Atenolol for Prevention of Aortic Dilation in Patients With Marfan Syndrome.
J Am Coll Cardiol. 2018 Oct 2;72(14):1613-1618.
doi: 10.1016/j.jacc.2018.07.052.
PubMed PMID: 30261963.
IF:16,834
Guala A, Rodriguez-Palomares J, Dux-Santoy L, Teixido-Tura G, Maldonado G, Galian L, Huguet M, Valente F, Gutiérrez L, González-Alujas T, Johnson KM, Wieben O, Sao Avilés A, Garcia-Dorado D, Evangelista A.
Influence of Aortic Dilation on the Regional Aortic Stiffness of Bicuspid Aortic Valve Assessed by 4-Dimensional Flow Cardiac Magnetic Resonance: Comparison With Marfan Syndrome and Degenerative Aortic Aneurysm.
JACC Cardiovasc Imaging. 2018 May 11. pii: S1936-878X(18)30300-0. doi: 10.1016/j.jcmg.2018.03.017. [Epub ahead of print]
PubMed PMID: 29778849.
IF:6,221
Gavara J, Rodriguez-Palomares JF, Valente F, Monmeneu JV, Lopez-Lereu MP,Bonanad C, Ferreira-Gonzalez I, Garcia Del Blanco B, Rodriguez-Garcia J,Mutuberria M, de Dios E, Rios-Navarro C, Perez-Sole N, Racugno P, Paya A, Minana
G, Canoves J, Pellicer M, Lopez-Fornas FJ, Barrabes J, Evangelista A, Nunez J,Chorro FJ, Garcia-Dorado D, Bodi V.
Prognostic Value of Strain by Tissue Tracking Cardiac Magnetic Resonance After ST-Segment Elevation Myocardial Infarction.
JACC Cardiovasc Imaging. 2018 Oct;11(10):1448-1457. doi: 10.1016/j.jcmg.2017.09.017.
Epub 2017 Dec 13. PubMed PMID: 29248649.
IF:6,221

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